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Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner

GSK3 (glycogen synthase kinase 3) is a conserved protein kinase governing numerous regulatory pathways. In Drosophila melanogaster, GSK3 is encoded by shaggy (sgg), which forms 17 annotated transcripts corresponding to 10 protein isoforms. Our goal was to demonstrate how differential sgg transcripti...

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Detalles Bibliográficos
Autores principales:	Trostnikov, Mikhail V., Roshina, Natalia V., Boldyrev, Stepan V., Veselkina, Ekaterina R., Zhuikov, Andrey A., Krementsova, Anna V., Pasyukova, Elena G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540023/ https://www.ncbi.nlm.nih.gov/pubmed/31060255 http://dx.doi.org/10.3390/ijms20092200

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