HER2 Upregulates ATF4 to Promote Cell Migration via Activation of ZEB1 and Downregulation of E-Cadherin

HER2 (human epidermal growth factor receptor 2) activation is critical in breast cancer development. HER2 promotes cell proliferation, angiogenesis, survival, and metastasis by activation of PI3K/Akt, Ras/MEK/ERK, and JAK/STAT pathways. However, beyond these signaling molecules, the key proteins und...

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Detalles Bibliográficos
Autores principales: Zeng, Peng, Sun, Shengnan, Li, Rui, Xiao, Zhi-Xiong, Chen, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540102/
https://www.ncbi.nlm.nih.gov/pubmed/31064130
http://dx.doi.org/10.3390/ijms20092223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540102/
https://www.ncbi.nlm.nih.gov/pubmed/31064130
http://dx.doi.org/10.3390/ijms20092223

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