Cargando…

HER2 Upregulates ATF4 to Promote Cell Migration via Activation of ZEB1 and Downregulation of E-Cadherin

HER2 (human epidermal growth factor receptor 2) activation is critical in breast cancer development. HER2 promotes cell proliferation, angiogenesis, survival, and metastasis by activation of PI3K/Akt, Ras/MEK/ERK, and JAK/STAT pathways. However, beyond these signaling molecules, the key proteins und...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeng, Peng, Sun, Shengnan, Li, Rui, Xiao, Zhi-Xiong, Chen, Hu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540102/ https://www.ncbi.nlm.nih.gov/pubmed/31064130 http://dx.doi.org/10.3390/ijms20092223

Ejemplares similares

ZEB1 and oncogenic Ras constitute a regulatory switch for stimulus‐dependent E‐cadherin downregulation
por: Otake, Shigeo, et al.
Publicado: (2020)

Slit2-Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E-cadherin
por: Zhao, Yuan, et al.
Publicado: (2016)

Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin
por: Zhang, Zefeng, et al.
Publicado: (2016)

Clinical implication of ZEB-1 and E-cadherin expression in hepatocellular carcinoma (HCC)
por: Hashiguchi, Motoyuki, et al.
Publicado: (2013)

Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT
por: Li, Qing, et al.
Publicado: (2021)

Exosomal miR-205-5p Improves Endometrial Receptivity by Upregulating E-Cadherin Expression through ZEB1 Inhibition
por: Yu, Seong-Lan, et al.
Publicado: (2023)

HNF-4α downregulation promotes tumor migration and invasion by regulating E-cadherin in renal cell carcinoma
por: Gao, Yaohui, et al.
Publicado: (2019)

An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer
por: Qin, Yong, et al.
Publicado: (2015)

LINC01012 upregulation promotes cervical cancer proliferation and migration via downregulation of CDKN2D
por: Zhang, Keyi, et al.
Publicado: (2023)

γ-secretase inhibitors, DAPT and RO4929097, promote the migration of Human Glioma Cells via Smad5-downregulated E-cadherin Expression
por: Chang, Shun-Fu, et al.
Publicado: (2021)

Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm
por: Chang, Ye Rim, et al.
Publicado: (2017)

PTTG1/ZEB1 Axis Regulates E-Cadherin Expression in Human Seminoma
por: Teveroni, Emanuela, et al.
Publicado: (2022)

E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer
por: Fonseca-Alves, Carlos Eduardo, et al.
Publicado: (2019)

ER stress activates TAp73α to promote colon cancer cell apoptosis via the PERK-ATF4 pathway
por: Sun, Shengnan, et al.
Publicado: (2023)

Upregulated expression levels of ADAM10 and EGFR and downregulated expression levels of E-cadherin in hepatocellular carcinomas
por: YUE, YUAN, et al.
Publicado: (2013)

Upregulated expression levels of ADAM10 and EGFR and downregulated expression levels of E-cadherin in hepatocellular carcinomas
Publicado: (2014)

Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch
por: Miro, Caterina, et al.
Publicado: (2019)

E-Cadherin Is Transcriptionally Activated via Suppression of ZEB1 Transcriptional Repressor by Small RNA-Mediated Gene Silencing
por: Mazda, Minami, et al.
Publicado: (2011)

Prognostic Role of Epithelial-Mesenchymal Transition Markers “E-Cadherin, β-Catenin, ZEB1, ZEB2 and p63” in Bladder Carcinoma
por: Moussa, Rabab Ahmed, et al.
Publicado: (2019)

Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin‐17A Which Downregulates E‐Cadherin
por: Hoh, Brian L., et al.
Publicado: (2018)

Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin
por: Lee, Joohyun, et al.
Publicado: (2016)

NAC1 Regulates Somatic Cell Reprogramming by Controlling Zeb1 and E-cadherin Expression
por: Faiola, Francesco, et al.
Publicado: (2017)

Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1
por: Park, Jun Bum, et al.
Publicado: (2020)

Role of epithelial-mesenchymal transition markers E-cadherin, N-cadherin, β-catenin and ZEB2 in laryngeal squamous cell carcinoma
por: Zhu, Guang-Jie, et al.
Publicado: (2018)

ATF3 suppresses ESCC via downregulation of ID1
por: Li, Jian, et al.
Publicado: (2016)

Galectin-14 Promotes Trophoblast Migration and Invasion by Upregulating the Expression of MMP-9 and N-Cadherin
por: Wang, Miaomiao, et al.
Publicado: (2021)

Loss of E-cadherin promotes prostate cancer metastasis via upregulation of metastasis-associated gene 1 expression
por: Fan, Liangsheng, et al.
Publicado: (2020)

Clinicopathological significance of ZEB-1 and E-cadherin proteins in patients with oral cavity squamous cell carcinoma
por: Yao, Xiaofeng, et al.
Publicado: (2017)

Comparison of Snail1, ZEB1, E-Cadherin Expression Levels in HPV-Induced Cervical Cancer
por: FARZANEHPOUR, Mahdieh, et al.
Publicado: (2020)

Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran
por: Nourmohammadi, Bahareh, et al.
Publicado: (2019)

RARγ-induced E-cadherin downregulation promotes hepatocellular carcinoma invasion and metastasis
por: Gan, Wen-Juan, et al.
Publicado: (2016)

BTBD7 Downregulates E-Cadherin and Promotes Epithelial-Mesenchymal Transition in Lung Cancer
por: Shu, Jie, et al.
Publicado: (2019)

TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression
por: Yao, Xin, et al.
Publicado: (2017)

Author Correction: Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch
por: Miro, Caterina, et al.
Publicado: (2020)

Tuberin-deficiency downregulates N-cadherin and upregulates vimentin in kidney tumor of TSC patients
por: Liang, Sitai, et al.
Publicado: (2014)

Upregulation of LncRNA‐HIT promotes migration and invasion of non‐small cell lung cancer cells by association with ZEB1
por: Jia, Xiaojing, et al.
Publicado: (2016)

Differential Downregulation of E-Cadherin and Desmoglein by Epidermal Growth Factor
por: Chavez, Miquella G., et al.
Publicado: (2012)

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer
por: Bae, Gab-Yong, et al.
Publicado: (2013)

Antitumor activity of RUNX3: Upregulation of E-cadherin and downregulation of the epithelial–mesenchymal transition in clear-cell renal cell carcinoma
por: Yang, Ruo-Nan, et al.
Publicado: (2022)

Modulation of E-cadherin expression promotes migration ability of esophageal cancer cells
por: Li, Shujun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_m4d4n7ikecfhe8qtnqco4ffrtd