Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B

Background: KDM5 enzymes are H3K4 specific histone demethylases involved in transcriptional regulation and DNA repair. These proteins are overexpressed in different kinds of cancer, including breast, prostate and bladder carcinomas, with positive effects on cancer proliferation and chemoresistance....

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Detalles Bibliográficos
Autores principales: Pippa, Simone, Mannironi, Cecilia, Licursi, Valerio, Bombardi, Luca, Colotti, Gianni, Cundari, Enrico, Mollica, Adriano, Coluccia, Antonio, Naccarato, Valentina, La Regina, Giuseppe, Silvestri, Romano, Negri, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540222/
https://www.ncbi.nlm.nih.gov/pubmed/31060229
http://dx.doi.org/10.3390/molecules24091739

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