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Chidamide, a histone deacetylase inhibitor, induces growth arrest and apoptosis in multiple myeloma cells in a caspase-dependent manner

Chidamide, a novel histone deacetylase (HDAC) inhibitor, induces antitumor effects in various types of cancer. The present study aimed to evaluate the cytotoxic effect of chidamide on multiple myeloma and the underlying mechanisms involved. Viability of multiple myeloma cells upon chidamide treatmen...

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Detalles Bibliográficos
Autores principales: Yuan, Xiang-Gui, Huang, Yu-Rong, Yu, Teng, Jiang, Hua-Wei, Xu, Yang, Zhao, Xiao-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540238/
https://www.ncbi.nlm.nih.gov/pubmed/31289512
http://dx.doi.org/10.3892/ol.2019.10301