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Gefitinib-mediated apoptosis is enhanced via inhibition of autophagy by chloroquine diphosphate in cutaneous squamous cell carcinoma cells

The development of cutaneous squamous cell carcinoma (cSCC) is associated with activation of the epidermal growth factor receptor (EGFR). EGFR-targeting presents a promising strategy for improving therapeutic efficacy. However, recent studies have suggested that tumours overexpressing EGFR depend on...

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Detalles Bibliográficos
Autores principales: Wang, Jianyu, Wang, Chaopeng, Hu, Xia, Yu, Chang, Zhou, Liang, Ding, Zhenhua, Zhou, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540344/
https://www.ncbi.nlm.nih.gov/pubmed/31289508
http://dx.doi.org/10.3892/ol.2019.10308