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Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study

OBJECTIVE: Neonatal sepsis still remains a significant cause of morbidity and mortality in developing countries. The prediction of the neonatal sepsis outcome depends on the anticipation from the clinical history, suspicion from clinical findings and confirmation by laboratory tests. This study aime...

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Detalles Bibliográficos
Autores principales: Bunduki, Gabriel Kambale, Adu-Sarkodie, Yaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540359/
https://www.ncbi.nlm.nih.gov/pubmed/31138330
http://dx.doi.org/10.1186/s13104-019-4346-5
Descripción
Sumario:OBJECTIVE: Neonatal sepsis still remains a significant cause of morbidity and mortality in developing countries. The prediction of the neonatal sepsis outcome depends on the anticipation from the clinical history, suspicion from clinical findings and confirmation by laboratory tests. This study aimed to determine the clinical outcome and isolated pathogens among neonates with sepsis in Butembo, Democratic Republic of the Congo. RESULTS: The most frequent bacteria related to a poor outcome were Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella spp. Most of isolated bacteria were found to be hospital-acquired infections. Therefore, adherence to infection prevention and control measures would reduce reduced rate of neonatal sepsis in our setting. The empiric antibiotic treatment should cover the spectrum of bacteria responsible of neonatal sepsis in Butembo, DRC. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4346-5) contains supplementary material, which is available to authorized users.