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Novel sporozoite-based ELISpot assay to assess frequency of parasite-specific B cells after vaccination with irradiated sporozoites

BACKGROUND: Whole parasite vaccination is an efficacious strategy to induce sterile immunity and to prevent malaria transmission. Understanding the mechanism and response of immune cells to vaccines plays a critical role in deciphering correlates of protection against infection and disease. Immunoas...

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Detalles Bibliográficos
Autores principales:	Atre, Tanmaya, Robinson, Tanisha M., Savransky, Tatyana, Dutta, Sheetij, Epstein, Judith E., Bergmann-Leitner, Elke S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540377/ https://www.ncbi.nlm.nih.gov/pubmed/31142328 http://dx.doi.org/10.1186/s12936-019-2819-6

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