Transient multifocal genomic crisis creating chromothriptic and non-chromothriptic rearrangements in prezygotic testicular germ cells

BACKGROUND: The co-occurrence of multiple de novo copy number variations (CNVs) is a rare phenomenon in the human genome. Recently, an “organismal CNV mutator phenotype” has been reported to result in transient genomic instability introducing multiple de novo CNVs in primary oocytes and early-stage...

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Detalles Bibliográficos
Autores principales: Hattori, Atsushi, Okamura, Kohji, Terada, Yumiko, Tanaka, Rika, Katoh-Fukui, Yuko, Matsubara, Yoichi, Matsubara, Keiko, Kagami, Masayo, Horikawa, Reiko, Fukami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540402/
https://www.ncbi.nlm.nih.gov/pubmed/31138192
http://dx.doi.org/10.1186/s12920-019-0526-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540402/
https://www.ncbi.nlm.nih.gov/pubmed/31138192
http://dx.doi.org/10.1186/s12920-019-0526-3

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