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Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle

BACKGROUND: BCG is the most widely used vaccine of all time and remains the only licensed vaccine for use against tuberculosis in humans. BCG also protects other species such as cattle against tuberculosis, but due to its incompatibility with current tuberculin testing regimens remains unlicensed. B...

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Detalles Bibliográficos
Autores principales: Mendum, Tom A., Chandran, Aneesh, Williams, Kerstin, Vordermeier, H. Martin, Villarreal-Ramos, Bernardo, Wu, H., Singh, Albel, Smith, Alex A., Butler, Rachel E., Prasad, Aravind, Bharti, Neeraj, Banerjee, Ruma, Kasibhatla, Sunitha M., Bhatt, Apoorva, Stewart, Graham R., McFadden, Johnjoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540422/
https://www.ncbi.nlm.nih.gov/pubmed/31138110
http://dx.doi.org/10.1186/s12864-019-5791-1