c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

Choroid plexus tumours (CPTs) account for 2–5% of brain tumours in children. They can spread along the neuraxis and can recur after treatment. Little is known about the molecular mechanisms underlying their formation and only few high fidelity mouse models of p53-deficient malignant CPTs are availab...

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Detalles Bibliográficos
Autores principales: Merve, Ashirwad, Zhang, Xinyu, Pomella, Nicola, Acquati, Serena, Hoeck, Joerg D., Dumas, Anaelle, Rosser, Gabriel, Li, Yichen, Jeyapalan, Jennie, Vicenzi, Silvia, Fan, Qianhai, Yang, Zeng Jie, Sabò, Arianna, Sheer, Denise, Behrens, Axel, Marino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540455/
https://www.ncbi.nlm.nih.gov/pubmed/31142360
http://dx.doi.org/10.1186/s40478-019-0739-x

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