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Associating somatic mutations to clinical outcomes: a pan-cancer study of survival time

We developed subclone multiplicity allocation and somatic heterogeneity (SMASH), a new statistical method for intra-tumor heterogeneity (ITH) inference. SMASH is tailored to the purpose of large-scale association studies with one tumor sample per patient. In a pan-cancer study of 14 cancer types, we...

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Detalles Bibliográficos
Autores principales:	Little, Paul, Lin, Dan-Yu, Sun, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540540/ https://www.ncbi.nlm.nih.gov/pubmed/31138328 http://dx.doi.org/10.1186/s13073-019-0643-9

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