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Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019

We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently,...

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Autores principales: Engsbro, Anne Line, Riis Jespersen, Hans Søe, Goldschmidt, Maria Ingeborg, Mollerup, Sarah, Worning, Peder, Pedersen, Martin Schou, Westh, Henrik, Schneider, Uffe Vest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540646/
https://www.ncbi.nlm.nih.gov/pubmed/31138366
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.21.1900289
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author Engsbro, Anne Line
Riis Jespersen, Hans Søe
Goldschmidt, Maria Ingeborg
Mollerup, Sarah
Worning, Peder
Pedersen, Martin Schou
Westh, Henrik
Schneider, Uffe Vest
author_facet Engsbro, Anne Line
Riis Jespersen, Hans Søe
Goldschmidt, Maria Ingeborg
Mollerup, Sarah
Worning, Peder
Pedersen, Martin Schou
Westh, Henrik
Schneider, Uffe Vest
author_sort Engsbro, Anne Line
collection PubMed
description We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases.
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spelling pubmed-65406462019-06-12 Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019 Engsbro, Anne Line Riis Jespersen, Hans Søe Goldschmidt, Maria Ingeborg Mollerup, Sarah Worning, Peder Pedersen, Martin Schou Westh, Henrik Schneider, Uffe Vest Euro Surveill Rapid Communication We describe a ceftriaxone-resistant Salmonella Typhi bacteraemia in a pregnant woman returning from a family visit in Pakistan. Whole genome sequencing confirmed similarity to a Pakistani outbreak clone. Pregnancy and unawareness of this outbreak delayed appropriate antibiotic therapy. Concurrently, we detected faecal carriage of a carbapenemase-producing Escherichia coli. Awareness of the ongoing outbreak should affect empiric treatment of typhoid fever and hygiene precautions in travellers returning from Pakistan. Meropenem may be warranted in severe cases. European Centre for Disease Prevention and Control (ECDC) 2019-05-23 /pmc/articles/PMC6540646/ /pubmed/31138366 http://dx.doi.org/10.2807/1560-7917.ES.2019.24.21.1900289 Text en This article is copyright of the authors or their affiliated institutions, 2019. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Engsbro, Anne Line
Riis Jespersen, Hans Søe
Goldschmidt, Maria Ingeborg
Mollerup, Sarah
Worning, Peder
Pedersen, Martin Schou
Westh, Henrik
Schneider, Uffe Vest
Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title_full Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title_fullStr Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title_full_unstemmed Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title_short Ceftriaxone-resistant Salmonella enterica serotype Typhi in a pregnant traveller returning from Karachi, Pakistan to Denmark, 2019
title_sort ceftriaxone-resistant salmonella enterica serotype typhi in a pregnant traveller returning from karachi, pakistan to denmark, 2019
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540646/
https://www.ncbi.nlm.nih.gov/pubmed/31138366
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.21.1900289
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