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Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles

The vast differences in material properties accessible via crosslinking of sidechain-functionalized polymers are driven by topology. For example, vulcanized rubbery networks feature intermolecular connections and loop topologies of various orders while single-chain nanoparticles (SCNPs) are comprise...

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Autores principales: Wang, Junpeng, Wang, Rui, Gu, Yuwei, Sourakov, Alexandra, Olsen, Bradley D., Johnson, Jeremiah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540913/
https://www.ncbi.nlm.nih.gov/pubmed/31191890
http://dx.doi.org/10.1039/c9sc01297d
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author Wang, Junpeng
Wang, Rui
Gu, Yuwei
Sourakov, Alexandra
Olsen, Bradley D.
Johnson, Jeremiah A.
author_facet Wang, Junpeng
Wang, Rui
Gu, Yuwei
Sourakov, Alexandra
Olsen, Bradley D.
Johnson, Jeremiah A.
author_sort Wang, Junpeng
collection PubMed
description The vast differences in material properties accessible via crosslinking of sidechain-functionalized polymers are driven by topology. For example, vulcanized rubbery networks feature intermolecular connections and loop topologies of various orders while single-chain nanoparticles (SCNPs) are comprised, in principle, entirely of primary loops. Despite this fact, precise quantification of loops in sidechain crosslinked polymers has not been accomplished. Here, it is demonstrated that by introducing cleavable linkers and mass labels onto the pendant functional groups of reactive polymers, the number of primary loops in sidechain crosslinked materials ranging from rubbery networks (gels) to soluble SCNPs can be precisely quantified. This study sheds new light on the topology of sidechain-crosslinked networks, providing design principles for augmenting the properties of this industrially and academically important class of materials through topological control.
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spelling pubmed-65409132019-06-12 Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles Wang, Junpeng Wang, Rui Gu, Yuwei Sourakov, Alexandra Olsen, Bradley D. Johnson, Jeremiah A. Chem Sci Chemistry The vast differences in material properties accessible via crosslinking of sidechain-functionalized polymers are driven by topology. For example, vulcanized rubbery networks feature intermolecular connections and loop topologies of various orders while single-chain nanoparticles (SCNPs) are comprised, in principle, entirely of primary loops. Despite this fact, precise quantification of loops in sidechain crosslinked polymers has not been accomplished. Here, it is demonstrated that by introducing cleavable linkers and mass labels onto the pendant functional groups of reactive polymers, the number of primary loops in sidechain crosslinked materials ranging from rubbery networks (gels) to soluble SCNPs can be precisely quantified. This study sheds new light on the topology of sidechain-crosslinked networks, providing design principles for augmenting the properties of this industrially and academically important class of materials through topological control. Royal Society of Chemistry 2019-05-01 /pmc/articles/PMC6540913/ /pubmed/31191890 http://dx.doi.org/10.1039/c9sc01297d Text en This journal is © The Royal Society of Chemistry 2019 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
spellingShingle Chemistry
Wang, Junpeng
Wang, Rui
Gu, Yuwei
Sourakov, Alexandra
Olsen, Bradley D.
Johnson, Jeremiah A.
Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title_full Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title_fullStr Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title_full_unstemmed Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title_short Counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
title_sort counting loops in sidechain-crosslinked polymers from elastic solids to single-chain nanoparticles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540913/
https://www.ncbi.nlm.nih.gov/pubmed/31191890
http://dx.doi.org/10.1039/c9sc01297d
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