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Current review of surgical management options for extremity bone sarcomas
Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
British Editorial Society of Bone and Joint Surgery
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/ https://www.ncbi.nlm.nih.gov/pubmed/31191985 http://dx.doi.org/10.1302/2058-5241.4.180048 |
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author | Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai |
author_facet | Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai |
author_sort | Cirstoiu, Catalin |
collection | PubMed |
description | Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation. The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty. Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres. Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article: EFORT Open Rev 2019;4:174-182. DOI: 10.1302/2058-5241.4.180048 |
format | Online Article Text |
id | pubmed-6540945 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | British Editorial Society of Bone and Joint Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-65409452019-06-12 Current review of surgical management options for extremity bone sarcomas Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai EFORT Open Rev Oncology Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation. The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty. Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres. Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article: EFORT Open Rev 2019;4:174-182. DOI: 10.1302/2058-5241.4.180048 British Editorial Society of Bone and Joint Surgery 2019-05-10 /pmc/articles/PMC6540945/ /pubmed/31191985 http://dx.doi.org/10.1302/2058-5241.4.180048 Text en © 2019 The author(s) https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) licence (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed. |
spellingShingle | Oncology Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai Current review of surgical management options for extremity bone sarcomas |
title | Current review of surgical management options for extremity bone sarcomas |
title_full | Current review of surgical management options for extremity bone sarcomas |
title_fullStr | Current review of surgical management options for extremity bone sarcomas |
title_full_unstemmed | Current review of surgical management options for extremity bone sarcomas |
title_short | Current review of surgical management options for extremity bone sarcomas |
title_sort | current review of surgical management options for extremity bone sarcomas |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/ https://www.ncbi.nlm.nih.gov/pubmed/31191985 http://dx.doi.org/10.1302/2058-5241.4.180048 |
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