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Current review of surgical management options for extremity bone sarcomas

Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation...

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Autores principales: Cirstoiu, Catalin, Cretu, Bogdan, Serban, Bogdan, Panti, Zsombor, Nica, Mihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Editorial Society of Bone and Joint Surgery 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/
https://www.ncbi.nlm.nih.gov/pubmed/31191985
http://dx.doi.org/10.1302/2058-5241.4.180048
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author Cirstoiu, Catalin
Cretu, Bogdan
Serban, Bogdan
Panti, Zsombor
Nica, Mihai
author_facet Cirstoiu, Catalin
Cretu, Bogdan
Serban, Bogdan
Panti, Zsombor
Nica, Mihai
author_sort Cirstoiu, Catalin
collection PubMed
description Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation. The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty. Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres. Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article: EFORT Open Rev 2019;4:174-182. DOI: 10.1302/2058-5241.4.180048
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spelling pubmed-65409452019-06-12 Current review of surgical management options for extremity bone sarcomas Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai EFORT Open Rev Oncology Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy. All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation. The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty. Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres. Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article: EFORT Open Rev 2019;4:174-182. DOI: 10.1302/2058-5241.4.180048 British Editorial Society of Bone and Joint Surgery 2019-05-10 /pmc/articles/PMC6540945/ /pubmed/31191985 http://dx.doi.org/10.1302/2058-5241.4.180048 Text en © 2019 The author(s) https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) licence (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed.
spellingShingle Oncology
Cirstoiu, Catalin
Cretu, Bogdan
Serban, Bogdan
Panti, Zsombor
Nica, Mihai
Current review of surgical management options for extremity bone sarcomas
title Current review of surgical management options for extremity bone sarcomas
title_full Current review of surgical management options for extremity bone sarcomas
title_fullStr Current review of surgical management options for extremity bone sarcomas
title_full_unstemmed Current review of surgical management options for extremity bone sarcomas
title_short Current review of surgical management options for extremity bone sarcomas
title_sort current review of surgical management options for extremity bone sarcomas
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/
https://www.ncbi.nlm.nih.gov/pubmed/31191985
http://dx.doi.org/10.1302/2058-5241.4.180048
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