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Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase

BACKGROUND: The tumor-like growth of the metacestode larvae of the tapeworm E. multilocularis causes human alveolar echinococcosis, a severe disease mainly affecting the liver. The germinative cells, a population of adult stem cells, are crucial for the larval growth and development of the parasite...

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Detalles Bibliográficos
Autores principales: Cheng, Zhe, Liu, Fan, Tian, Huimin, Xu, Zhijian, Chai, Xiaoli, Luo, Damin, Wang, Yanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541280/
https://www.ncbi.nlm.nih.gov/pubmed/31095613
http://dx.doi.org/10.1371/journal.pntd.0007425