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Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase
BACKGROUND: The tumor-like growth of the metacestode larvae of the tapeworm E. multilocularis causes human alveolar echinococcosis, a severe disease mainly affecting the liver. The germinative cells, a population of adult stem cells, are crucial for the larval growth and development of the parasite...
Autores principales: | Cheng, Zhe, Liu, Fan, Tian, Huimin, Xu, Zhijian, Chai, Xiaoli, Luo, Damin, Wang, Yanhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541280/ https://www.ncbi.nlm.nih.gov/pubmed/31095613 http://dx.doi.org/10.1371/journal.pntd.0007425 |
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