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A novel understanding of postoperative complications: In vitro study of the impact of propofol on epigenetic modifications in cholinergic genes
BACKGROUND: Propofol is a widely used anaesthetic drug with advantageous operating conditions and recovery profile. However, propofol could have long term effects on neuronal cells and is associated with post-operative delirium (POD). In this context, one of the contributing factors to the pathogene...
Autores principales: | Holtkamp, Caroline, Koos, Björn, Unterberg, Matthias, Rahmel, Tim, Bergmann, Lars, Bazzi, Zainab, Bazzi, Maha, Bukhari, Hassan, Adamzik, Michael, Rump, Katharina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541299/ https://www.ncbi.nlm.nih.gov/pubmed/31141559 http://dx.doi.org/10.1371/journal.pone.0217269 |
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