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Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection

The low pathogenicity and replicative potential of HIV-2 are still poorly understood. We investigated whether HIV-2 reservoirs might follow the peculiar distribution reported in models of attenuated HIV-1/SIV infections, i.e. limited infection of central-memory CD4 T lymphocytes (TCM). Antiretrovira...

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Detalles Bibliográficos
Autores principales: Samri, Assia, Charpentier, Charlotte, Diallo, Mariama Sadjo, Bertine, Mélanie, Even, Sophie, Morin, Véronique, Oudin, Anne, Parizot, Christophe, Collin, Gilles, Hosmalin, Anne, Cheynier, Rémi, Thiébaut, Rodolphe, Matheron, Sophie, Collin, Fideline, Zoorob, Rima, Brun-Vézinet, Françoise, Autran, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541300/
https://www.ncbi.nlm.nih.gov/pubmed/31095640
http://dx.doi.org/10.1371/journal.ppat.1007758