Novel (2-amino-4-arylimidazolyl)propanoic acids and pyrrolo[1,2-c]imidazoles via the domino reactions of 2-amino-4-arylimidazoles with carbonyl and methylene active compounds

The unexpectedly uncatalyzed reaction between 2-amino-4-arylimidazoles, aromatic aldehydes and Meldrum’s acid has selectively led to the corresponding Knoevenagel–Michael adducts containing a free amino group in the imidazole fragment. The adducts derived from Meldrum’s acid have been smoothly conve...

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Detalles Bibliográficos
Autores principales: Lipson, Victoria V, Pavlovska, Tetiana L, Svetlichnaya, Nataliya V, Poryvai, Anna A, Gorobets, Nikolay Yu, Van der Eycken, Erik V, Konovalova, Irina S, Shiskina, Svetlana V, Borisov, Alexander V, Musatov, Vladimir I, Mazepa, Alexander V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541323/
https://www.ncbi.nlm.nih.gov/pubmed/31164941
http://dx.doi.org/10.3762/bjoc.15.101

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