Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions

Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles....

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Detalles Bibliográficos
Autores principales: Barreto, Angélica de Fátima S, Andrade, Carlos Kleber Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541343/
https://www.ncbi.nlm.nih.gov/pubmed/31164928
http://dx.doi.org/10.3762/bjoc.15.88
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author Barreto, Angélica de Fátima S
Andrade, Carlos Kleber Z
author_facet Barreto, Angélica de Fátima S
Andrade, Carlos Kleber Z
author_sort Barreto, Angélica de Fátima S
collection PubMed
description Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps.
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spelling pubmed-65413432019-06-04 Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions Barreto, Angélica de Fátima S Andrade, Carlos Kleber Z Beilstein J Org Chem Review Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps. Beilstein-Institut 2019-04-15 /pmc/articles/PMC6541343/ /pubmed/31164928 http://dx.doi.org/10.3762/bjoc.15.88 Text en Copyright © 2019, Barreto and Andrade https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Barreto, Angélica de Fátima S
Andrade, Carlos Kleber Z
Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title_full Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title_fullStr Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title_full_unstemmed Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title_short Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
title_sort synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541343/
https://www.ncbi.nlm.nih.gov/pubmed/31164928
http://dx.doi.org/10.3762/bjoc.15.88
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