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The association of elevated maternal genetic risk scores for hypertension, type 2 diabetes and obesity and having a child with a congenital heart defect
BACKGROUND: Maternal hypertension, type 2 diabetes (T2D) and obesity are associated with an increased risk of having offspring with conotruncal heart defects (CTDs). Prior studies have identified sets of single nucleotide polymorphisms (SNPs) that are associated with risk for each of these three adu...
Autores principales: | Kaplinski, Michelle, Taylor, Deanne, Mitchell, Laura E., Hammond, Dorothy A., Goldmuntz, Elizabeth, Agopian, A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541344/ https://www.ncbi.nlm.nih.gov/pubmed/31141530 http://dx.doi.org/10.1371/journal.pone.0216477 |
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