Cargando…
Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress
The immune system supports brain plasticity and homeostasis, yet it is prone to changes following psychological stress. Thus, it remains unclear whether and how stress-induced immune alterations contribute to the development of mental pathologies. Here, we show that following severe stress in mice,...
Autores principales: | Kertser, A., Baruch, K., Deczkowska, A., Weiner, A., Croese, T., Kenigsbuch, M., Cooper, I., Tsoory, M., Ben-Hamo, S., Amit, I., Schwartz, M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541460/ https://www.ncbi.nlm.nih.gov/pubmed/31149632 http://dx.doi.org/10.1126/sciadv.aav4111 |
Ejemplares similares
-
Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology
por: Baruch, Kuti, et al.
Publicado: (2015) -
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
por: Deczkowska, Aleksandra, et al.
Publicado: (2017) -
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
por: Rosenzweig, Neta, et al.
Publicado: (2019) -
CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions
por: Shifrut, Eric, et al.
Publicado: (2013) -
Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress
por: Ben-Yehuda, Hila, et al.
Publicado: (2019)