Defining early SIV replication and dissemination dynamics following vaginal transmission

Understanding HIV transmission is critical to guide the development of prophylactic interventions to prevent infection. We used a nonhuman primate (NHP) model with a synthetic swarm of sequence-tagged variants of SIVmac239 (“SIVmac239X”) and scheduled necropsy during primary infection (days 3 to 14...

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Detalles Bibliográficos
Autores principales: Deleage, Claire, Immonen, Taina T., Fennessey, Christine M., Reynaldi, Arnold, Reid, Carolyn, Newman, Laura, Lipkey, Leslie, Schlub, Timothy E., Camus, Celine, O’Brien, Sean, Smedley, Jeremy, Conway, Jessica M., Del Prete, Gregory Q., Davenport, Miles P., Lifson, Jeffrey D., Estes, Jacob D., Keele, Brandon F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541462/
https://www.ncbi.nlm.nih.gov/pubmed/31149634
http://dx.doi.org/10.1126/sciadv.aav7116

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