Control of antiviral innate immune response by protein geranylgeranylation

The mitochondrial antiviral signaling protein (MAVS) orchestrates host antiviral innate immune response to RNA virus infection. However, how MAVS signaling is controlled to eradicate virus while preventing self-destructive inflammation remains obscure. Here, we show that protein geranylgeranylation,...

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Detalles Bibliográficos
Autores principales: Yang, Shigao, Harding, Alfred T., Sweeney, Catherine, Miao, David, Swan, Gregory, Zhou, Connie, Jiang, Zhaozhao, Fitzgerald, Katherine A., Hammer, Gianna, Bergo, Martin O., Kroh, Heather K., Lacy, D. Borden, Sun, Chunxiang, Glogauer, Michael, Que, Loretta G., Heaton, Nicholas S., Wang, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541464/
https://www.ncbi.nlm.nih.gov/pubmed/31149635
http://dx.doi.org/10.1126/sciadv.aav7999

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