Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective

PURPOSE: To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament. METHODS: Systematic review and cost-effectiveness analysis. RESULTS: The available evidence does not show any significant difference in clinical effectiveness between...

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Detalles Bibliográficos
Autores principales: Waugh, Norman, Mistry, Hema, Metcalfe, Andrew, Colquitt, Jill, Loveman, Emma, Royle, Pamela, Smith, Nick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Knee
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541577/
https://www.ncbi.nlm.nih.gov/pubmed/30903218
http://dx.doi.org/10.1007/s00167-019-05477-4
Descripción
Sumario:PURPOSE: To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament. METHODS: Systematic review and cost-effectiveness analysis. RESULTS: The available evidence does not show any significant difference in clinical effectiveness between autografts and allografts. Given that, only a cost analysis is provided, which shows that allografts are more costly. CONCLUSION: Given the lack of any benefit of allografts over autografts, autografts should be preferred on cost grounds, if available. However, there may be situations where an allograft is indicated, for example, in multiple ligament reconstructions. LEVEL OF EVIDENCE: IV. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00167-019-05477-4) contains supplementary material, which is available to authorized users.

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