Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective

PURPOSE: To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament. METHODS: Systematic review and cost-effectiveness analysis. RESULTS: The available evidence does not show any significant difference in clinical effectiveness between...

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Autores principales: Waugh, Norman, Mistry, Hema, Metcalfe, Andrew, Colquitt, Jill, Loveman, Emma, Royle, Pamela, Smith, Nick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Knee
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541577/
https://www.ncbi.nlm.nih.gov/pubmed/30903218
http://dx.doi.org/10.1007/s00167-019-05477-4
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author Waugh, Norman
Mistry, Hema
Metcalfe, Andrew
Colquitt, Jill
Loveman, Emma
Royle, Pamela
Smith, Nick A.
author_facet Waugh, Norman
Mistry, Hema
Metcalfe, Andrew
Colquitt, Jill
Loveman, Emma
Royle, Pamela
Smith, Nick A.
author_sort Waugh, Norman
collection PubMed
description PURPOSE: To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament. METHODS: Systematic review and cost-effectiveness analysis. RESULTS: The available evidence does not show any significant difference in clinical effectiveness between autografts and allografts. Given that, only a cost analysis is provided, which shows that allografts are more costly. CONCLUSION: Given the lack of any benefit of allografts over autografts, autografts should be preferred on cost grounds, if available. However, there may be situations where an allograft is indicated, for example, in multiple ligament reconstructions. LEVEL OF EVIDENCE: IV. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00167-019-05477-4) contains supplementary material, which is available to authorized users.
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spelling pubmed-65415772019-06-14 Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective Waugh, Norman Mistry, Hema Metcalfe, Andrew Colquitt, Jill Loveman, Emma Royle, Pamela Smith, Nick A. Knee Surg Sports Traumatol Arthrosc Knee PURPOSE: To review the relative cost-effectiveness of allografts and autografts in reconstruction of the posterior cruciate ligament. METHODS: Systematic review and cost-effectiveness analysis. RESULTS: The available evidence does not show any significant difference in clinical effectiveness between autografts and allografts. Given that, only a cost analysis is provided, which shows that allografts are more costly. CONCLUSION: Given the lack of any benefit of allografts over autografts, autografts should be preferred on cost grounds, if available. However, there may be situations where an allograft is indicated, for example, in multiple ligament reconstructions. LEVEL OF EVIDENCE: IV. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00167-019-05477-4) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2019-03-22 2019 /pmc/articles/PMC6541577/ /pubmed/30903218 http://dx.doi.org/10.1007/s00167-019-05477-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Knee
Waugh, Norman
Mistry, Hema
Metcalfe, Andrew
Colquitt, Jill
Loveman, Emma
Royle, Pamela
Smith, Nick A.
Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title_full Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title_fullStr Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title_full_unstemmed Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title_short Allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
title_sort allografts in reconstruction of the posterior cruciate ligament: a health economics perspective
topic Knee
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541577/
https://www.ncbi.nlm.nih.gov/pubmed/30903218
http://dx.doi.org/10.1007/s00167-019-05477-4
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