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Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin

The lung lineage master regulator gene, Thyroid Transcription Factor-1 (TTF-1, also known as NKX2-1), is used as a marker by pathologists to identify lung adenocarcinomas since TTF-1 is expressed in 60 ~ 70% of lung ADs. Much research has been conducted to investigate roles of TTF-1 in lung cancer b...

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Detalles Bibliográficos
Autores principales: Phelps, Cody A., Lindsey-Boltz, Laura, Sancar, Aziz, Mu, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541604/
https://www.ncbi.nlm.nih.gov/pubmed/31142791
http://dx.doi.org/10.1038/s41598-019-44549-w