Varying levels of X chromosome coalescence in female somatic cells alters the balance of X-linked dosage compensation and is implicated in female-dominant systemic lupus erythematosus

The three-dimensional organization of the genome in mammalian interphase nuclei is intrinsically linked to the regulation of gene expression. Whole chromosome territories and their encoded gene loci occupy preferential positions within the nucleus that changes according to the expression profile of...

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Detalles Bibliográficos
Autores principales: Laskowski, Agnieszka I., Neems, Daniel S., Laster, Kyle, Strojny-Okyere, Chelsee, Rice, Ellen L., Konieczna, Iwona M., Voss, Jessica H., Mathew, James M., Leventhal, Joseph R., Ramsey-Goldman, Rosalind, Smith, Erica D., Kosak, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541617/
https://www.ncbi.nlm.nih.gov/pubmed/31142749
http://dx.doi.org/10.1038/s41598-019-44229-9

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