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Berberine alleviates hyperglycemia by targeting hepatic glucokinase in diabetic db/db mice

Berberine (BBR) is a widely used anti-diabetic agent, and liver glucokinase (GK) has been reported to be involved. However, the mechanisms of BBR in regulating GK are still unknown. Here, we found that BBR upregulated GK immunofluorescence expression in AML12 cells cultured in high glucose and incre...

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Detalles Bibliográficos
Autores principales:	Li, Meng, Dang, Yanqi, Li, Qiong, Zhou, Wenjun, Zuo, Jianping, Yao, Zemin, Zhang, Li, Ji, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541623/ https://www.ncbi.nlm.nih.gov/pubmed/31142783 http://dx.doi.org/10.1038/s41598-019-44576-7

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