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Transcriptomics Analysis Reveals New Insights into the Roles of Notch1 Signaling on Macrophage Polarization

Naïve macrophages (Mφ) polarize in response to various environmental cues to a spectrum of cells that have distinct biological functions. The extreme ends of the spectrum are classified as M1 and M2 macrophages. Previously, we demonstrated that Notch1 deficiency promotes Tgf-β2 dependent M2-polariza...

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Detalles Bibliográficos
Autores principales: Hans, Chetan P., Sharma, Neekun, Sen, Sidharth, Zeng, Shuai, Dev, Rishabh, Jiang, Yuexu, Mahajan, Advitiya, Joshi, Trupti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541629/
https://www.ncbi.nlm.nih.gov/pubmed/31142802
http://dx.doi.org/10.1038/s41598-019-44266-4