Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors

The family of long noncoding mitochondrial RNAs (ncmtRNAs), comprising sense (SncmtRNA), and antisense (ASncmtRNA-1 and ASncmtRNA-2) members, are differentially expressed according to cell proliferative status; SncmtRNA is expressed in all proliferating cells, while ASncmtRNAs are expressed in norma...

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Detalles Bibliográficos
Autores principales: Fitzpatrick, Christopher, Bendek, Maximiliano F., Briones, Macarena, Farfán, Nicole, Silva, Valeria A., Nardocci, Gino, Montecino, Martín, Boland, Anne, Deleuze, Jean-François, Villegas, Jaime, Villota, Claudio, Silva, Verónica, Lobos-Gonzalez, Lorena, Borgna, Vincenzo, Barrey, Eric, Burzio, Luis O., Burzio, Verónica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541642/
https://www.ncbi.nlm.nih.gov/pubmed/31142736
http://dx.doi.org/10.1038/s41419-019-1649-3

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