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Type I interferons in host defence and inflammatory diseases

Type I interferons (IFN) can have dual and opposing roles in immunity, with effects that are beneficial or detrimental to the individual depending on whether IFN pathway activation is transient or sustained. Determinants of IFN production and its functional consequences include the nature of the mic...

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Detalles Bibliográficos
Autores principales: Crow, Mary K., Ronnblom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541752/
https://www.ncbi.nlm.nih.gov/pubmed/31205729
http://dx.doi.org/10.1136/lupus-2019-000336