Cargando…
miR-142-3p suppresses uveal melanoma by targeting CDC25C, TGFβR1, GNAQ, WASL, and RAC1
Purpose: Uveal melanoma (UM) is the most frequent metastatic ocular tumor in adults. Therapeutic intervention remains ineffective since none of the novel procedures used to treat this disease increased survival rates. To deal with this limitation, additional studies are required to clarify its patho...
Autores principales: | Peng, Dewei, Dong, Jing, Zhao, Yunping, Peng, Xiaomei, Tang, Jingjing, Chen, Xiaoyan, Wang, Lihua, Hu, Dan-Ning, Reinach, Peter S, Qu, Jia, Yan, Dongsheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541795/ https://www.ncbi.nlm.nih.gov/pubmed/31213897 http://dx.doi.org/10.2147/CMAR.S206461 |
Ejemplares similares
-
MITF deficiency accelerates GNAQ-driven uveal melanoma
por: Phelps, Grace B., et al.
Publicado: (2022) -
microRNA miR-142-3p Inhibits Breast Cancer Cell Invasiveness by Synchronous Targeting of WASL, Integrin Alpha V, and Additional Cytoskeletal Elements
por: Schwickert, Alexander, et al.
Publicado: (2015) -
Frequent somatic mutations of GNAQ in uveal melanoma and blue nevi
por: Van Raamsdonk, Catherine D., et al.
Publicado: (2008) -
Oncogenic GNAQ and GNA11 Mutations in Uveal Melanoma in Chinese
por: Xu, Xiaolin, et al.
Publicado: (2014) -
Mutation spectrum in GNAQ and GNA11 in Chinese uveal melanoma
por: Zhang, Edward D, et al.
Publicado: (2019)