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Genetic determinants of circulating haptoglobin concentration

Haptoglobin (Hp) is a major plasma acute-phase glycoprotein, which binds free haemoglobin to neutralize its toxicity. The HP gene exists as two copy number variants (CNV), Hp1 and HP2, which differ in two ways: serum Hp level and functional differences in Hp protein products. Both mechanisms may und...

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Detalles Bibliográficos
Autores principales:	Kazmi, Nabila, Koda, Yoshiro, Ndiaye, Ndeye Coumba, Visvikis-Siest, Sophie, Morton, Matthew J, Gaunt, Tom R, Galea, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541910/ https://www.ncbi.nlm.nih.gov/pubmed/30898509 http://dx.doi.org/10.1016/j.cca.2019.03.1617

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