HNF1α Controls Liver Lipid Metabolism and Insulin Resistance via Negatively Regulating the SOCS-3-STAT3 Signaling Pathway

This study is aimed at evaluating the effects, functions, and mechanism of HNF1α on hepatic glycolipid metabolism. In this study, free fatty acid- (FFA-) induced steatosis of hepatocyte liver cell LO2 was used as an in vitro model. The methods of Oil Red O staining, RT-qPCR, western blot, and immuno...

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Detalles Bibliográficos
Autores principales: Tan, Jiaorong, Xu, Jiahong, Wei, Guohua, Zhang, Lijuan, Sun, Long'e, Wang, Guangyu, Li, Fei, Jiang, Fengxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541945/
https://www.ncbi.nlm.nih.gov/pubmed/31223625
http://dx.doi.org/10.1155/2019/5483946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541945/
https://www.ncbi.nlm.nih.gov/pubmed/31223625
http://dx.doi.org/10.1155/2019/5483946

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