Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals

Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.

Detalles Bibliográficos
Autores principales: Donaldson, Anne D., Nieduszynski, Conrad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541995/
https://www.ncbi.nlm.nih.gov/pubmed/31146781
http://dx.doi.org/10.1186/s13059-019-1719-y
Descripción
Sumario:Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.

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