Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals

Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.

Detalles Bibliográficos
Autores principales: Donaldson, Anne D., Nieduszynski, Conrad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541995/
https://www.ncbi.nlm.nih.gov/pubmed/31146781
http://dx.doi.org/10.1186/s13059-019-1719-y
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author Donaldson, Anne D.
Nieduszynski, Conrad A.
author_facet Donaldson, Anne D.
Nieduszynski, Conrad A.
author_sort Donaldson, Anne D.
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description Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance.
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spelling pubmed-65419952019-06-03 Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals Donaldson, Anne D. Nieduszynski, Conrad A. Genome Biol Research Highlight Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implications of this remarkable technological advance. BioMed Central 2019-05-30 /pmc/articles/PMC6541995/ /pubmed/31146781 http://dx.doi.org/10.1186/s13059-019-1719-y Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Highlight
Donaldson, Anne D.
Nieduszynski, Conrad A.
Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title_full Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title_fullStr Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title_full_unstemmed Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title_short Genome-wide analysis of DNA replication timing in single cells: Yes! We’re all individuals
title_sort genome-wide analysis of dna replication timing in single cells: yes! we’re all individuals
topic Research Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541995/
https://www.ncbi.nlm.nih.gov/pubmed/31146781
http://dx.doi.org/10.1186/s13059-019-1719-y
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