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Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease
In addition to protective “immune response”, sepsis is characterized by destructive “endothelial response” of the host, leading to endotheliopathy and its molecular dysfunction. Complement activation generates membrane attack complex (MAC). MAC causes channel formation to the cell membrane of pathog...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542012/ https://www.ncbi.nlm.nih.gov/pubmed/31160889 http://dx.doi.org/10.1186/s12959-019-0198-4 |