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A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma

BACKGROUND: Adult T-cell leukemia/lymphoma (ATL) is a peripheral T-cell malignancy caused by long-term human T-cell leukemia virus type I (HTLV-1) infection. Survivin-responsive, conditionally replicating adenoviruses regulated by multiple tumor-specific factors (Surv.m-CRAs), in which the expressio...

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Detalles Bibliográficos
Autores principales:	Suzuki, Shinsuke, Kofune, Hiroki, Uozumi, Kimiharu, Yoshimitsu, Makoto, Arima, Naomichi, Ishitsuka, Kenji, Ueno, Shin-ichi, Kosai, Ken-ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542078/ https://www.ncbi.nlm.nih.gov/pubmed/31142289 http://dx.doi.org/10.1186/s12885-019-5730-1

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