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Serp-2, a virus-derived apoptosis and inflammasome inhibitor, attenuates liver ischemia-reperfusion injury in mice
BACKGROUND: Ischemia-reperfusion injury (IRI) is an antigen-independent, innate immune response to arterial occlusion and ischemia with subsequent paradoxical exacerbation after reperfusion. IRI remains a critical problem after vessel occlusion and infarction or during harvest and surgery in transpl...
Autores principales: | Yaron, Jordan R., Chen, Hao, Ambadapadi, Sriram, Zhang, Liqiang, Tafoya, Amanda M., Munk, Barbara H., Wakefield, Dara N., Fuentes, Jorge, Marques, Bruno J., Harripersaud, Krishna, Bartee, Mee Yong, Davids, Jennifer A., Zheng, Donghang, Rand, Kenneth, Dixon, Lisa, Moyer, Richard W., Clapp, William L., Lucas, Alexandra R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542089/ https://www.ncbi.nlm.nih.gov/pubmed/31160886 http://dx.doi.org/10.1186/s12950-019-0215-1 |
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