CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice

Although rare, CALM/AF10 is a chromosomal rearrangement found in immature T-cell acute lymphoblastic leukemia (T-ALL), acute myeloid leukemia, and mixed phenotype acute leukemia of T/myeloid lineages with poor prognosis. Moreover, this translocation is detected in 50% of T-ALL patients with gamma/de...

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Detalles Bibliográficos
Autores principales: Lange, A.P., Almeida, L.Y., Araújo Silva, C.L., Scheucher, P.S., Chahud, F., Krause, A., Bohlander, S.K., Rego, E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542091/
https://www.ncbi.nlm.nih.gov/pubmed/31141090
http://dx.doi.org/10.1590/1414-431X20198424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542091/
https://www.ncbi.nlm.nih.gov/pubmed/31141090
http://dx.doi.org/10.1590/1414-431X20198424

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