Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model

The Zika virus (ZIKV) outbreak and its link to microcephaly triggered a public health concern. To examine antibody response in a patient infected with ZIKV, we used single-cell PCR to clone 31 heavy and light chain-paired monoclonal antibodies (mAbs) that bind to ZIKV envelope (E) proteins isolated...

Descripción completa

Detalles Bibliográficos
Autores principales: Niu, Xuefeng, Zhao, Lingzhai, Qu, Linbing, Yao, Zhipeng, Zhang, Fan, Yan, Qihong, Zhang, Shengnan, Liang, Renshan, Chen, Peihai, Luo, Jia, Xu, Wei, Lv, Huibin, Liu, Xinglong, Lei, Hui, Yi, Changhua, Li, Pingchao, Wang, Qian, Wang, Yang, Yu, Lei, Zhang, Xiaoyan, Bryan, L. Aubrey, Davidson, Edgar, Doranz, j. Benjamin, Feng, Liqiang, Pan, Weiqi, Zhang, Fuchun, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542155/
https://www.ncbi.nlm.nih.gov/pubmed/31130109
http://dx.doi.org/10.1080/22221751.2019.1614885

Ejemplares similares

Ejemplares similares