Cargando…

Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal

BACKGROUND: Trichomonas vaginalis and genital Mycoplasmas are two synergistic pathogens, but in many settings, limited data on the co-infection by Trichomonas and Mycoplasma are available. OBJECTIVE: This study aimed at assessing Mycoplasma prevalence and its association with Trichomonas vaginalis a...

Descripción completa

Detalles Bibliográficos
Autores principales: Tine, Roger C., Dia, Lamine, Sylla, Khadime, Sow, Doudou, Lelo, Souleye, Ndour, Cheikh T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542312/
https://www.ncbi.nlm.nih.gov/pubmed/31161092
http://dx.doi.org/10.4103/tp.TP_50_18
_version_ 1783422912403865600
author Tine, Roger C.
Dia, Lamine
Sylla, Khadime
Sow, Doudou
Lelo, Souleye
Ndour, Cheikh T.
author_facet Tine, Roger C.
Dia, Lamine
Sylla, Khadime
Sow, Doudou
Lelo, Souleye
Ndour, Cheikh T.
author_sort Tine, Roger C.
collection PubMed
description BACKGROUND: Trichomonas vaginalis and genital Mycoplasmas are two synergistic pathogens, but in many settings, limited data on the co-infection by Trichomonas and Mycoplasma are available. OBJECTIVE: This study aimed at assessing Mycoplasma prevalence and its association with Trichomonas vaginalis among women with vaginal discharge. MATERIALS AND METHODS: A retrospective analysis of laboratory records (2012 and 2013) from patients referred at the Fann teaching hospital in Dakar Senegal for vaginal discharge was carried out. Detection of genital mycoplasmas was based on the commercial Kit Mycoplasma Duo Bio-Rad™ using endo-cervical swabs. Vaginal swabs were collected and examined using optic microscopy with 40x magnification to detect T. vaginalis. RESULTS: Overall, data from 1257 women were analysed. Prevalence of Mycoplasma hominis represented 57.4%, 95%CI(54.6-60.1), versus 54.9%, 95%CI(52.1-57.5) for Ureaplasma urealyticum. Trichomonas vaginalis infection was observed with a frequency of 3%. Out of the 50 patients with trichomoniasis, 76% of them were co-infected by Mycoplasma hominis and patients with Trichomonas vaginalis had an increased risk of acquiring Mycoplasma infection (adjusted OR:2.5, 95%CI(1.2-5.2);p=0.02)). CONCLUSION: Trichomonas vaginalis and Mycoplasmas are two closely associated pathogens in the urogenital tract of women. This clinically significant symbiotic action may require systematic screening of Mycoplasma among patients with trichomoniasis for optimal management of sexually transmitted infections.
format Online
Article
Text
id pubmed-6542312
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-65423122019-06-03 Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal Tine, Roger C. Dia, Lamine Sylla, Khadime Sow, Doudou Lelo, Souleye Ndour, Cheikh T. Trop Parasitol Original Article BACKGROUND: Trichomonas vaginalis and genital Mycoplasmas are two synergistic pathogens, but in many settings, limited data on the co-infection by Trichomonas and Mycoplasma are available. OBJECTIVE: This study aimed at assessing Mycoplasma prevalence and its association with Trichomonas vaginalis among women with vaginal discharge. MATERIALS AND METHODS: A retrospective analysis of laboratory records (2012 and 2013) from patients referred at the Fann teaching hospital in Dakar Senegal for vaginal discharge was carried out. Detection of genital mycoplasmas was based on the commercial Kit Mycoplasma Duo Bio-Rad™ using endo-cervical swabs. Vaginal swabs were collected and examined using optic microscopy with 40x magnification to detect T. vaginalis. RESULTS: Overall, data from 1257 women were analysed. Prevalence of Mycoplasma hominis represented 57.4%, 95%CI(54.6-60.1), versus 54.9%, 95%CI(52.1-57.5) for Ureaplasma urealyticum. Trichomonas vaginalis infection was observed with a frequency of 3%. Out of the 50 patients with trichomoniasis, 76% of them were co-infected by Mycoplasma hominis and patients with Trichomonas vaginalis had an increased risk of acquiring Mycoplasma infection (adjusted OR:2.5, 95%CI(1.2-5.2);p=0.02)). CONCLUSION: Trichomonas vaginalis and Mycoplasmas are two closely associated pathogens in the urogenital tract of women. This clinically significant symbiotic action may require systematic screening of Mycoplasma among patients with trichomoniasis for optimal management of sexually transmitted infections. Wolters Kluwer - Medknow 2019 2019-05-22 /pmc/articles/PMC6542312/ /pubmed/31161092 http://dx.doi.org/10.4103/tp.TP_50_18 Text en Copyright: © 2019 Tropical Parasitology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Tine, Roger C.
Dia, Lamine
Sylla, Khadime
Sow, Doudou
Lelo, Souleye
Ndour, Cheikh T.
Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title_full Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title_fullStr Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title_full_unstemmed Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title_short Trichomonas vaginalis and Mycoplasma infections among women with vaginal discharge at Fann teaching hospital in Senegal
title_sort trichomonas vaginalis and mycoplasma infections among women with vaginal discharge at fann teaching hospital in senegal
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542312/
https://www.ncbi.nlm.nih.gov/pubmed/31161092
http://dx.doi.org/10.4103/tp.TP_50_18
work_keys_str_mv AT tinerogerc trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal
AT dialamine trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal
AT syllakhadime trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal
AT sowdoudou trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal
AT lelosouleye trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal
AT ndourcheikht trichomonasvaginalisandmycoplasmainfectionsamongwomenwithvaginaldischargeatfannteachinghospitalinsenegal