Characterisation of Deubiquitylating Enzymes in the Cellular Response to High-LET Ionizing Radiation and Complex DNA Damage

PURPOSE: Ionizing radiation, particular high-linear energy transfer (LET) radiation, can induce complex DNA damage (CDD) wherein 2 or more DNA lesions are induced in close proximity, which contributes significantly to the cell killing effects. However, knowledge of the enzymes and mechanisms involve...

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Detalles Bibliográficos
Autores principales: Carter, Rachel J., Nickson, Catherine M., Thompson, James M., Kacperek, Andrzej, Hill, Mark A., Parsons, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier, Inc 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542414/
https://www.ncbi.nlm.nih.gov/pubmed/30851349
http://dx.doi.org/10.1016/j.ijrobp.2019.02.053

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