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Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man

INTRODUCTION: Chest wall masses are caused by various entities and have diverse aetiologies. A careful history and physical examination are crucial to establish the correct diagnosis. CASE REPORT: A 77-year-old man presented with depressive mood, anorexia (weight loss of 20 kg) and a 1-month history...

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Autores principales: Brazão, Sofia Gomes, Costa, Regina, Albano, Miguel Nico, Jesus, Nelson, Carvalho, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542496/
https://www.ncbi.nlm.nih.gov/pubmed/31157188
http://dx.doi.org/10.12890/2019_001113
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author Brazão, Sofia Gomes
Costa, Regina
Albano, Miguel Nico
Jesus, Nelson
Carvalho, Armando
author_facet Brazão, Sofia Gomes
Costa, Regina
Albano, Miguel Nico
Jesus, Nelson
Carvalho, Armando
author_sort Brazão, Sofia Gomes
collection PubMed
description INTRODUCTION: Chest wall masses are caused by various entities and have diverse aetiologies. A careful history and physical examination are crucial to establish the correct diagnosis. CASE REPORT: A 77-year-old man presented with depressive mood, anorexia (weight loss of 20 kg) and a 1-month history of a non-painful breast lump with well-defined contours, which was about 6 cm in diameter. There was no history of trauma. Computed tomography of the thorax revealed a collection of liquid in the left anterior thoracic wall, associated with discontinuity of the 4th left costal cartilage, and upper left lobe cavitation, suggesting pulmonary tuberculosis. The patient was started on quadruple therapy with anti-tuberculosis drugs and discharged after a negative smear. CONCLUSION: In this case, the indolent onset of unspecific symptoms made it difficult to reach a diagnosis of pulmonary tuberculosis, which was confirmed by positive culture and imaging. A breast lump in an elderly patient with unspecific clinical manifestations is an unusual presentation of pulmonary tuberculosis. It is important to be aware of rib invasion and exclude tuberculosis in a patient with a chest wall mass. As tuberculosis is treatable, early diagnosis is vital as diagnostic delay can lead to contagion. LEARNING POINTS: Chest wall tuberculosis is a rare complication of pulmonary tuberculosis. As smears and acid-fast bacilli cultures are often negative, polymerase chain reaction and imaging should be performed. Tuberculosis should be treated with first-line drugs; the role of surgery is still controversial.
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spelling pubmed-65424962019-05-31 Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man Brazão, Sofia Gomes Costa, Regina Albano, Miguel Nico Jesus, Nelson Carvalho, Armando Eur J Case Rep Intern Med Articles INTRODUCTION: Chest wall masses are caused by various entities and have diverse aetiologies. A careful history and physical examination are crucial to establish the correct diagnosis. CASE REPORT: A 77-year-old man presented with depressive mood, anorexia (weight loss of 20 kg) and a 1-month history of a non-painful breast lump with well-defined contours, which was about 6 cm in diameter. There was no history of trauma. Computed tomography of the thorax revealed a collection of liquid in the left anterior thoracic wall, associated with discontinuity of the 4th left costal cartilage, and upper left lobe cavitation, suggesting pulmonary tuberculosis. The patient was started on quadruple therapy with anti-tuberculosis drugs and discharged after a negative smear. CONCLUSION: In this case, the indolent onset of unspecific symptoms made it difficult to reach a diagnosis of pulmonary tuberculosis, which was confirmed by positive culture and imaging. A breast lump in an elderly patient with unspecific clinical manifestations is an unusual presentation of pulmonary tuberculosis. It is important to be aware of rib invasion and exclude tuberculosis in a patient with a chest wall mass. As tuberculosis is treatable, early diagnosis is vital as diagnostic delay can lead to contagion. LEARNING POINTS: Chest wall tuberculosis is a rare complication of pulmonary tuberculosis. As smears and acid-fast bacilli cultures are often negative, polymerase chain reaction and imaging should be performed. Tuberculosis should be treated with first-line drugs; the role of surgery is still controversial. SMC Media Srl 2019-05-20 /pmc/articles/PMC6542496/ /pubmed/31157188 http://dx.doi.org/10.12890/2019_001113 Text en © EFIM 2019 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Articles
Brazão, Sofia Gomes
Costa, Regina
Albano, Miguel Nico
Jesus, Nelson
Carvalho, Armando
Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title_full Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title_fullStr Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title_full_unstemmed Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title_short Breast Lump: A Rare Presentation of Tuberculosis in an Elderly Man
title_sort breast lump: a rare presentation of tuberculosis in an elderly man
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542496/
https://www.ncbi.nlm.nih.gov/pubmed/31157188
http://dx.doi.org/10.12890/2019_001113
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