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Chaetomium atrobrunneum causing human eumycetoma: The first report

In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains’ morphological and cytological features. However, further aerobic culture of the black grains generate...

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Autores principales: Mhmoud, Najwa A., Santona, Antonella, Fiamma, Maura, Siddig, Emmanuel Edwar, Deligios, Massimo, Bakhiet, Sahar Mubarak, Rubino, Salvatore, Fahal, Ahmed Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542518/
https://www.ncbi.nlm.nih.gov/pubmed/31145740
http://dx.doi.org/10.1371/journal.pntd.0007276
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author Mhmoud, Najwa A.
Santona, Antonella
Fiamma, Maura
Siddig, Emmanuel Edwar
Deligios, Massimo
Bakhiet, Sahar Mubarak
Rubino, Salvatore
Fahal, Ahmed Hassan
author_facet Mhmoud, Najwa A.
Santona, Antonella
Fiamma, Maura
Siddig, Emmanuel Edwar
Deligios, Massimo
Bakhiet, Sahar Mubarak
Rubino, Salvatore
Fahal, Ahmed Hassan
author_sort Mhmoud, Najwa A.
collection PubMed
description In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains’ morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungus identified as C. atrobrunneum by conventional morphological methods and by internal transcribed spacer 2 (ITS2) ribosomal RNA gene sequencing. This is the first-ever report of C. atrobrunneum as a eumycetoma-causative organism of black grain eumycetoma. It is essential that the causative organism is identified to the species level, as this is important for proper patient management and to predict treatment outcome and prognosis.
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spelling pubmed-65425182019-06-17 Chaetomium atrobrunneum causing human eumycetoma: The first report Mhmoud, Najwa A. Santona, Antonella Fiamma, Maura Siddig, Emmanuel Edwar Deligios, Massimo Bakhiet, Sahar Mubarak Rubino, Salvatore Fahal, Ahmed Hassan PLoS Negl Trop Dis Symposium In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains’ morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungus identified as C. atrobrunneum by conventional morphological methods and by internal transcribed spacer 2 (ITS2) ribosomal RNA gene sequencing. This is the first-ever report of C. atrobrunneum as a eumycetoma-causative organism of black grain eumycetoma. It is essential that the causative organism is identified to the species level, as this is important for proper patient management and to predict treatment outcome and prognosis. Public Library of Science 2019-05-30 /pmc/articles/PMC6542518/ /pubmed/31145740 http://dx.doi.org/10.1371/journal.pntd.0007276 Text en © 2019 Mhmoud et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Symposium
Mhmoud, Najwa A.
Santona, Antonella
Fiamma, Maura
Siddig, Emmanuel Edwar
Deligios, Massimo
Bakhiet, Sahar Mubarak
Rubino, Salvatore
Fahal, Ahmed Hassan
Chaetomium atrobrunneum causing human eumycetoma: The first report
title Chaetomium atrobrunneum causing human eumycetoma: The first report
title_full Chaetomium atrobrunneum causing human eumycetoma: The first report
title_fullStr Chaetomium atrobrunneum causing human eumycetoma: The first report
title_full_unstemmed Chaetomium atrobrunneum causing human eumycetoma: The first report
title_short Chaetomium atrobrunneum causing human eumycetoma: The first report
title_sort chaetomium atrobrunneum causing human eumycetoma: the first report
topic Symposium
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542518/
https://www.ncbi.nlm.nih.gov/pubmed/31145740
http://dx.doi.org/10.1371/journal.pntd.0007276
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