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SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Modified vaccinia virus Ankara (MVA) is the leading poxvirus vector for development of vaccines against diverse infectious diseases. This distinction is based on high expression of proteins and good immunogenicity despite an inability to assemble infectious progeny in human cells, which together pro...

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Detalles Bibliográficos
Autores principales: Liu, Ruikang, Mendez-Rios, Jorge D., Peng, Chen, Xiao, Wei, Weisberg, Andrea S., Wyatt, Linda S., Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542542/
https://www.ncbi.nlm.nih.gov/pubmed/31145755
http://dx.doi.org/10.1371/journal.ppat.1007710

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