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Dysfunctional peripheral T follicular helper cells dominate in people with impaired influenza vaccine responses: Results from the FLORAH study

Antigen-primed cluster of differentiation (CD) 4(+) T follicular helper (Tfh) cells interact with B cells in the germinal centers (GCs) of lymph nodes to generate vaccine-induced antibody (Ab) responses. In the circulation, peripheral Tfh (pTfh) cells, a subset of memory CD4 T cells, serve as surrog...

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Detalles Bibliográficos
Autores principales:	Pallikkuth, Suresh, de Armas, Lesley R., Rinaldi, Stefano, George, Varghese K., Pan, Li, Arheart, Kristopher L., Pahwa, Rajendra, Pahwa, Savita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542545/ https://www.ncbi.nlm.nih.gov/pubmed/31100059 http://dx.doi.org/10.1371/journal.pbio.3000257

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