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Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells

Maturity-onset diabetes of the young (MODY) is a heterozygous monogenic diabetes; more than 14 disease genes have been identified. However, the pathogenesis of MODY is not fully understood because the patients’ pancreatic beta cells are inaccessible. To elucidate the pathology of MODY, we establishe...

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Detalles Bibliográficos
Autores principales: Yabe, Shigeharu G., Nishida, Junko, Fukuda, Satsuki, Takeda, Fujie, Nasiro, Kiyoko, Yasuda, Kazuki, Iwasaki, Naoko, Okochi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542550/
https://www.ncbi.nlm.nih.gov/pubmed/31145732
http://dx.doi.org/10.1371/journal.pone.0217110